Hands-on training on fast product and process development for continuous freeze-drying of biologics, ATMP’s and LNP based formulations
For the third time RheaVita organizes its famous Lyo course!
We welcome everyone at our new location in Ghent for 3 days filled with mainly new insights, presentation of the latest developments and the possibility to network with peers in the picturesque city of Ghent.
For this year we have decided to focus on how you can achieve fast formulation and process development with limited amount of materials using the RheaVita continuous freeze-drying single vial unit.
Participants will be given hands-on training.
We will present in detail the continuous freeze-drying process, how to make use of PAT tools to monitor and actively control your product and process from R&D to production, and how to number up from lab development to GMP production by using continuous freeze-drying technology.
The hands-on applications will include biologics, ATMP’s and LNP based formulations. Case studies will be presented by Coriolis and Etherna.
The hands-on applications will be based on biologics, ATMP’s and LNP based formulations. Case studies will be presented by Ghent University, Coriolis and Etherna.
Registration and info: https://rheavita.com/in-house-event/
Agenda:
Day 1: Continuous and controlled freeze-drying
Basic and fundamentals of continuous and controlled freeze-drying
Introduction to RheaVita’s continuous and controlled freeze-drying technology (including DEMO)
Reception
Day 2: Hands-on training on fast product and process development
Fast formulation and process development with limited material consumption
Process monitoring and control at vial level during continuous freeze-drying
Continuous Freeze-Drying Technology as enabler for biopharmaceuticals and ATMPs
Case study: Fast process and formulation development of continuous freeze-dried LNP-based formulations – George Dakwar (Etherna)
Case study: The Impact of Formulation Composition and Process Settings of Traditional Batch Versus Continuous Freeze-Drying On Protein Aggregation – Brecht Vanbillemont (Coriolis Pharma)
Hands-on fast formulation and process development by participants using RheaVita’s single vial unit (SVU) and software platforms by means of biologics, ATMP’s and LNP-based formulations case studies
Networking dinner in Ghent
Day 3: Towards continuous freeze-drying GMP production
Fast transfer from SVU to GMP-Flex
Continuous Freeze-Drying in GMP facility
Speakers:
Dr. Brecht Vanbillemont (Coriolis)
Dr. George Dakwar (Etherna)
Mrs. Sofie Meulewaeter (Ghent University)
Prof. Thomas De Beer (RheaVita)
Ir. Jos Corver (RheaVita)
Dr. Pieter-Jan Van Bockstal (RheaVita)